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Research Shows Modern Humans’ Brain Size has Shrunk by 20%

by Patrick Holford(more info)

listed in dna gene expression, originally published in issue 294 - May 2024

 

Both brain size and IQ are falling in modern humans, coinciding with a big increase in mental illness. What we eat is to blame, says Professor Michael Crawford, co-author, with David Marsh, of his latest book ‘The Shrinking Brain’. Sir David Attenborough is convinced he is right.

 

Shrinking Brain BOOK COVER

https://www.amazon.co.uk/Shrinking-Brain-Michael-Crawford/dp/1915465125

 

IQ scores have also been steadily falling for the past few decades. Norwegian researchers, headed by Ole Rogeberg, a senior research fellow at the Ragnar Frisch Center for Economic Research in Norway, analysed the IQ scores of Norwegian men born between 1962 and 1991 and found that scores steadily decreased among those born after 1975.[1] “Similar studies in Denmark, Britain, France, the Netherlands, Finland and Estonia have demonstrated a similar downward trend in IQ scores,” says Rogeberg. “The decline is due to environmental factors;

This coincides with a change in the Western diet away from fat, towards carbohydrate and sugar, based on the mistaken belief that it was fat, not sugar, that was causing heart disease and that we should all eat a low-fat diet. Since then, our IQ scores have been dropping by about 7 per cent per generation.”

“We are heading for an idiocracy” says Professor Crawford who is Director of the Institute of Brain Chemistry and Human Nutrition. “Currently one in five of the world’s children and adolescents have a mental health condition.”[2]  If this trend continues, by 2080 he predicts that more than a third of the world’s population will be borderline mentally retarded.

The World Health Organisation report says “there has been a 13% rise in mental health conditions. One in eight now suffers from mental illness. Incidence of depression is through the roof. Last year in the UK there were over 100 million prescriptions for antidepressants.”

Crawford is convinced it is the modern-day diet that is causing us to dumb down. “Our genome is adapted to eating the wild foods we ate during our species’ evolution. Today’s diet bears no resemblance to this.”

In his book, The Shrinking Brain, he says “Our ancestors evolved a unique 1,600cc brain evolving from our ancestral 350cc brain of the chimpanzee, despite our genome only differing by 1.5%.[3] This could only have happened with the provision of brain-specific building nutrients from land and sea. There is incontrovertible evidence of early Homo sapiens exploiting the marine food web in coastal Africa.” In other words, we were the waterside ape who became smart, with bigger brains, by eating mussels, oysters, crabs and fish.

 

Fish

 

Professor Crawford discovered, in 1971, that the brains of all mammals are rich in omega-3 DHA. The size of their brain varied according to their dietary supply of DHA found in seafood. A dolphin, for example, has a 1,700cc brain, slightly larger than ours, while a lion has a 320cc brain about that of a chimpanzee. “The mix of wild land and aquatic foods powered by the encephalization of the brain from the 340cc of the chimp to the 1,500-1,700 of Cro-Magnon. DHA is not only involved in signalling but it stimulates gene expression in the brain so the rich aquatic food sources constantly, every day, would have powered the increase in brain size and function.” says Crawford.

“Today’s diet contains less than a tenth of the omega-3 fats that our ancestors ate and this is having dire consequences on mental health. Increased rates of depression, autism, ADHD and dementia are all strongly linked to a lack of seafood. Increased intake from eating fish or supplementing omega-3 fish oils reduces dementia risk by 20 per cent.[4] While a plant-based diet has many benefits, those who eat no fish are especially vulnerable and must supplement omega-3 DHA, derived from algae. The only way to be sure you have enough is to get a blood test to specifically test your levels.” Says Patrick Holford, CEO of the FoodfortheBrain.org charity.  

 

Hyperlink to: https://vimeo.com/808289297

Food for the Brain

 

The charity has just launched a simple ‘do it at home’ pin-prick test that can give you a clear indication of your Omega-3 levels, alongside a Cognitive Function Test, that can help identify what’s driving future risk and show you how to dementia-proof your diet and lifestyle.

Canadian neuroscientist and brain expert Professor Stephen Cunnane at the University of Sherbrook in Canada agrees “A shore-based diet, i.e., fish, molluscs, crustaceans, frogs, bird's eggs and aquatic plants, provides the richest known dietary sources of brain selective nutrients.” says Cunnane. “Change in diet away from marine foods is the likely explanation for this decrease in brain size.”  

 

Coastal

 

Sir David Attenborough, a supporter of the waterside ape theory, agrees “Gathering molluscs is far easier than chasing elephants and wildebeests across the savannah.”

Today, under 5 per cent of children achieve the basic requirement for omega-3 from seafood.[5]

Professor Michael Crawford, who is a visiting professor at Imperial College’s Chelsea & Westminster campus and science advisor to the charity foodforthebrain.org, was part of the team that has recently established that, if a pregnant woman lacks omega-3 DHA she produces a substitute fat, oleic acid, to fill the baby’s brain. But it doesn’t work. Levels of oleic acid in a pregnant woman’s blood predicted preterm birth which carries the highest risk of developmental brain problems and mental deficits in their offspring, as well as a risk of learning and cognitive disabilities. Low omega-3 and B vitamins in mothers increase the risk for lower IQ, learning and emotional problems in children [6].

Anyone concerned about their levels of Omega-3 can now test their levels with a home test kit provided by the charity foodforthebrain.org,  which is offered alongside a free Cognitive Function Test, that assesses how well your diet is supporting your brain heath. A new study shows that the higher the omega-3 index and DHA, which is what Food for the Brain measures, the greater both the brain size and the cognition of older people.[7] Brain size predicts cognitive abilities.

The decline of man

Brain size is worked out from skull capacity. Homo sapiens skulls dating back to 29,000 years ago had a brain capacity of 1,660cc. By 10,000 years ago it was around 1,500cc or 1.5 kilograms. The average brain size today is a fifth smaller, at 1,336cc. Brain size may have started to shrink 10,000 years ago, coinciding with mankind developing more land-based agriculture and eating less marine food along rivers and coasts.

 “We are inviting people to join our ‘citizen science’ study to track the impact of diet and Omega-3 on cognitive function over time.” says the charity’s CEO, Patrick Holford, a brain health expert. “I’m convinced we are digging our graves with a knife and fork and our brains and mental health are suffering as a result. Alzheimer’s, which is preventable, is also a direct consequence of this.”

The Food for the Brain Foundation

The Food for the Brain Foundation (foodforthebrain.org) is an educational and research charity, focussing on dementia prevention. Its free online validated Cognitive Function Test, followed by the Dementia Risk Index questionnaire assessing eight drivers of dementia, including ‘brain fats’ and ‘low carbs & GL’ thus identifying those eating too many carbs and not enough brain fats, then advising them what to do.

Supporting Research

IQ Falling

Bratsberg B, Rogeberg O. Flynn effect and its reversal are both environmentally caused. Proc Natl Acad Sci USA;115(26): 6674-6678.  doi: 10.1073/pnas.1718793115. Epub Jun 11 2018 . PMID: 29891660; PMCID: PMC6042097. Jun 26 2018.

Decrease in Brain Size

Cunnane SC, Crawford MA. Energetic and nutritional constraints on infant brain development: implications for brain expansion during human evolution. J Hum Evol;77:88-98. doi: 10.1016/j.jhevol.2014.05.001. Epub Jun 11 2014 . PMID: 24928072. Dec 2014.

Mental Health Rising

https://www.who.int/publications/i/item/9789240049338

Omega-3 Predicts Cognitive Problems In Children

Montgomery P, Burton JR, Sewell RP, Spreckelsen TF, Richardson AJ. Low blood long chain omega-3 fatty acids in UK children are associated with poor cognitive performance and behavior: a cross-sectional analysis from the DOLAB study. PLoS One.; 8(6):e66697. doi:10.1371/journal.pone.0066697.  Jun 24 2013.

Omega-3 Predicts Risk For Dementia And Cognitive Decline

Wei BZ, Li L, Dong CW, Tan CC; Alzheimer’s Disease Neuroimaging Initiative; Xu W. The Relationship of Omega-3 Fatty Acids with Dementia and Cognitive Decline: Evidence from Prospective Cohort Studies of Supplementation, Dietary Intake, and Blood Markers. Am J Clin Nutr;117(6):1096-1109. doi: 10.1016/j.ajcnut.2023.04.001. Epub Apr 5 2023 . PMID: 37028557; PMCID: PMC10447496. Jun 2023.

Omega-3 Levels Predict Brain Size in Older People

Loong, S.; Barnes, S.; Gatto, N.M.; Chowdhury, S.; Lee, G.J. Omega-3 Fatty Acids, Cognition, and Brain Volume in Older Adults. Brain Sci.2023,13,1278.  DOI:10.3390/brainsci13091278    https://pubmed.ncbi.nlm.nih.gov/37759879/  

References

  1. Bratsberg B, Rogeberg O. Flynn effect and its reversal are both environmentally caused. Proc Natl Acad Sci U S A;115(26):6674-6678. doi: 10.1073/pnas.1718793115. Epub Jun 11 2018. . PMID: 29891660; PMCID: PMC6042097. Jun 26 2018
  2. https://www.who.int/publications/i/item/9789240049338
  3. Cunnane SC, Crawford MA. Energetic and nutritional constraints on infant brain development: implications for brain expansion during human evolution. J Hum Evol. 77:88-98. doi: 10.1016/j.jhevol.2014.05.001. Epub Jun 11 2014. . PMID: 24928072. Dec 2014.
  4. 4. Wei BZ, Li L, Dong CW, Tan CC; Alzheimer’s Disease Neuroimaging Initiative; Xu W. The Relationship of Omega-3 Fatty Acids with Dementia and Cognitive Decline: Evidence from Prospective Cohort Studies of Supplementation, Dietary Intake, and Blood Markers. Am J Clin Nutr;117(6):1096-1109. doi: 10.1016/j.ajcnut.2023.04.001. Epub Apr 5 2023 . PMID: 37028557; PMCID: PMC10447496. Jun 2023.
  5. 5. Kranz, S.; Jones, N.R.V.; Monsivais, P. Intake Levels of Fish in the UK Paediatric Population. Nutrients 2017, 9, 392. https://doi.org/10.3390/nu9040392
  6. Montgomery P, Burton JR, Sewell RP, Spreckelsen TF, Richardson AJ. Low blood long chain omega-3 fatty acids in UK children are associated with poor cognitive performance and behavior: a cross-sectional analysis from the DOLAB study. PLoS One.; 8(6):e66697. doi:10.1371/journal.pone.0066697. Jun 24 2013. . Erratum in: PLoS One.2013.;8(9); see also Veena SR, Krishnaveni GV, Srinivasan K, Wills AK, Muthayya S, Kurpad AV, Yajnik CS, Fall CH. Higher maternal plasma folate but not vitamin B-12 concentrations during pregnancy are associated with better cognitive function scores in 9- to 10- year-old children in South India. J Nutr ;140(5):1014-22. doi: 10.3945/jn.109.118075. Epub Mar 24 2010. . PMID: 20335637; PMCID: PMC3672847. May 2010.; see also McNulty H, Rollins M, Cassidy T, Caffrey A, Marshall B, Dornan J, McLaughlin M, McNulty BA, Ward M, Strain JJ, Molloy AM, Lees-Murdock DJ, Walsh CP, Pentieva K. Effect of continued folic acid supplementation beyond the first trimester of pregnancy on cognitive performance in the child: a follow-up study from a randomized controlled trial (FASSTT Offspring Trial). BMC Med. ;17(1):196. doi: 10.1186/s12916-019-1432-4. PMID: 31672132; PMCID: PMC6823954. Oct 31 2019.
  7. Loong, S.; Barnes, S.; Gatto, N.M.; Chowdhury, S.; Lee, G.J. Omega-3 Fatty Acids, Cognition, and Brain Volume in Older Adults. Brain Sci.2023,13,1278. DOI:3390/brainsci13091278   https://pubmed.ncbi.nlm.nih.gov/37759879/  

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About Patrick Holford

Patrick Holford BSc DipION FBANT NTCRP is Nutrition and Mental Health Expert & Founder of the Institute for Optimum Nutrition Advice, VitaminC4Covid, and the charitable Food for the Brain Foundation, which studies how to prevent Alzheimer’s Disease. Patrick reads thousands of studies a year assimilating the latest health breakthroughs and turn them into practical advice to make it easy for everyone to live a healthy life. He is author of over 45 health books translated into 30 languages. https://www.patrickholford.com/ 

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