Listed in Issue 114


SANTELMANN and HOWARD, Holistisk Senter, Oslo, Norway,, have reviewed (58 references) yeast, yeast antigens and yeast metabolic products as possible triggers for IBS. Abstract: Many patients with irritable bowel syndrome (IBS) suffer from numerous symptoms not covered by the Rome criteria for IBS, and current empirical treatment regimens fail to address these persistent debilitating 'IBS associated symptoms'. These symptoms are similar to other symptom complexes like chronic fatigue and the so-called 'Candida syndrome', and many sufferers seek help from complementary and alternative medicine. The possible role of Candida and yeasts in non-immune compromised individuals is disputed and is the subject of this review. Even if the involvement of yeasts in the aetiology of IBS still remains unclear, there is increasing evidence for yeasts being able to cause IBS-symptoms in sensitized patients via Candida products, antigens and cross-antigens. But more research is needed before antifungal treatment can be recommended as a first line treatment for IBS.






Santelmann H, Howard JM. Yeast metabolic products, yeast antigens and yeasts as possible triggers for irritable bowel syndrome. European Journal of Gastroenterology & Hepatology 17 (1): 21-26, Jan 2005.

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