Positive Health Online

Abstract

LIU and COLLEAGUES, (1)School of Public Health, Shanxi Medical University, Taiyuan, China; (2)School of Management, Shanxi Medical University, Taiyuan, China; (3)Department of Respiratory and Critical Care Medicine, Qingdao Central ; Hospital, University of Health and Rehabilitation Sciences, Qingdao, China; (4)Department of Pediatrics, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, China.; (5)Shenzhen Maternity and Child Healthcare Hospital, Shenzhen, China.; (6)School of Public Policy and Administration, Xi'an Jiaotong University, Xi'an, China.; (7)School of Rehabilitation Science and Engineering, University of Health and Rehabilitation Sciences, Qingdao, China. fengyihui@uor.edu.cn . explored the relationship between dietary vitamin A intake from different sources and NAFLD risk among American adults.

Background

Non-alcoholic fatty liver disease (NAFLD) has become an urgent public health issue with high global prevalence, but data on NAFLD are inconsistent. The association of total dietary vitamin A intake with the NAFLD risk was not well documented in previous studies. To explore the relationship between dietary vitamin A intake from different sources and NAFLD risk among American adults.

Methodology

Data were collected from the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2014. Logistic regression and restricted cubic spline models were used to estimate the relationship between total dietary vitamin A intake and NAFLD risk. 6,613 adult participants were included.

Results

After adjusting potential confounders, the odds ratios (ORs) with 95% confidence intervals (CIs) of NAFLD for the highest quartile intake of total vitamin A, preformed vitamin A, provitamin A carotenoids were respectively 0.86 (0.69-1.06), 0.97 (0.74-1.28), and 0.78 (0.61-0.99), compared to the lowest quartile. Stratifying gender and age, provitamin A carotenoids intake was inversely associated with NAFLD risk in females and participants aged < 45 years. Dose-response analysis indicated a linear negative relationship between provitamin A carotenoids intake and Non-alcoholic fatty liver disease (NAFLD) risk. Provitamin A carotenoids intake was inversely associated with NAFLD, especially in women and those aged < 45 years among adult American. © 2024. The Author(s). Conflict of interest statement: The authors declare no competing interests.

Conclusion

References

Liu C(1)(2), Sun X(3), Peng J(4), Yu H(5), Lu J(6), Feng Y(7). Association between dietary vitamin A intake from different sources and non-alcoholic fatty liver disease among adults. Sci Rep.  ;14(1):1851. doi: 10.1038/s41598-024-52077-5. Jan 22 2024.