Research: LIANG and colleagues, Pek

Listed in Issue 28


LIANG and colleagues, Peking Union Medical College, Union Hospital, Beijing studied the relationship of lipid peroxides in coronary heart disease, in patients with and without diabetes, and their Syndrome in Chinese Medicines. @m:METHODS: 57 patients with coronary heart disease (CHD), including 21 cases with diabetes and 36 without and 30 healthy people were involved in this study. The activity of red blood cell superoxide dismutase (RBC-SOD), serum malondialdehydr (MDA), plasma 6-keto-prostaglandin F 1 alpha (6-keto-PGF 1 alpha) and thromboxane B2 (TXB2) were determined, characteristics of Syndrome Differentiation and typing observed. @r: Compared to the healthy people, the activity of RBC-SOD, 6-keto-PGF 1 alpha in CHD patients were significantly lower, and the levels of TXB2 and MDA were significantly higher. The TXB2 levels were significantly higher in CHD diabetic patients compared to nondiabetic patients, and the RBC-SOD activity were significantly lower. There were strongly positive correlations between levels of serum MDA and those of blood sugar, TXB2, TG and BMI in CHD diabetic patients. There were strong negative correlations between levels of serum MDA and plasma 6-keto-PGF 1 alpha. @c: These results suggest that the lipoperoxides metabolic abnormality was more serious in diabetic CHD patients compared with nondiabetic patients. The main Syndrome of CHD with diabetes was Qi-Yin Deficiency with Blood Stasis; the non-diabetic Syndrome was Qi Deficiency with Blood Stasis.






Liang XC et al. Study on relationship of lipid peroxide in coronary heart disease with and without diabetes. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih 16(1): 29-31. Jan 1996.

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