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Research: GOLDFARB, Department o
Listed in Issue 46
Abstract
GOLDFARB, Department of Exercise and Sport Science, University of North Carolina-Greensboro 27402-6169 USA write that several mechanisms have been proposed to explain the aetiology of exercise-induced muscle damage . The authors review (74 references)the field of muscle damage.
Background
Methodology
Results
and Discussion: Free radical mediated processes appear to be an important component of the inflammatory mediated response and have been demonstrated to be a contributing factor in the loss of calcium homeostasis within the cell. Therefore, intervention of free-radical mediated processes is one of the proposed treatments for preventing or reducing the extent of this damage. Antioxidants work by quenching free radicals; the traditional dietary antioxidants most commonly studied are vitamins C, E and beta-carotene . Other nutritional agents, such as isoflavonoids and other phytochemicals have been proposed to contain antioxidant properties. The author briefly reviews these agents and their putative roles, proven or proposed, in the prevention of oxidative stress and muscle damage.
Conclusion
References
Goldfarb AH. Nutritional antioxidants as therapeutic and preventive modalities in exercise-induced muscle damage. Canadian Journal of Applied Physiology 24(3): 249-66. Jun 1999.
