Listed in Issue 245


De ALMEIDA and COLLEAGUES (1)University of Ribeirão Preto, Eugênio Ferrante, 170, Ribeirão Preto - SP - Brazil, CEP 14027-150 AssessED drinking water fortification with iron and/or ascorbic acid as  a strategy to control iron-deficiency anaemia and iron deficiency.



Randomized blind clinical study, fortifying drinking water to 153 pre-school children during 3 months, with iron and ascorbic acid (A), ascorbic acid (B) or plain water (C). Haemoglobin (Hb), mean corpuscular volume (MCV) and ferritin were measured.


Within the groups, Hb raised in all three groups, MCV in A and B and ferritin in A. The difference between time points 0 and 1 was significant between A and B for Hb, when A and B were compared with C for MCV and when A was compared with either B or C for ferritin.


Water fortification is efficient in controlling iron deficiency and anaemia. Iron stores' recovery depends on a more effective offer of iron. Water fortification must be preceded by a careful assessment of the previous nutritional status.


de Almeida CA(1), De Mello ED, Ramos AP, João CA, João CR, Dutra-de-Oliveira JE. Assessment of drinking water fortification with iron plus ascorbic Acid or ascorbic Acid alone in daycare centers as a strategy to control iron-deficiency anemia and iron deficiency: a randomized blind clinical study.  J Trop Pediatr. 60(1):40-6. Feb 2014. doi: 10.1093/tropej/fmt071. Epub Aug 20 2013.

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