Research: CALÒ and COLLEAGUES,

Listed in Issue 243

Abstract

CALÒ and COLLEAGUES,  (1)Division of Cardiology, Policlinico Casilino, ASL Rome B, Rome, Italy. Electronic address: leonardo.calo@tin.it. (2)Division of Cardiology, Policlinico Casilino, ASL Rome B, Rome, Italy investigated the benefits of fish oils in the prevention of  cardiovascular diseases.

Background

In the past years, in vitro and animal studies have demonstrated several direct and indirect anti-arrhythmic effects of n-3 polyunsaturated fatty acids (n-3 PUFAs), at least in part mediated by anti-oxidant, anti-inflammatory and anti-fibrotic properties.

Methodology

Several epidemiological and clinical studies have been conducted to investigate the eventual benefits of fish oils in the prevention of cardiovascular diseases.

Results

The aim of this paper is to critically review current evidence on the anti-arrhythmic effects of n-3 PUFAs in the prevention of sudden cardiac death (SCD) and atrial fibrillation (AF).

Conclusion

Published data are conflicting, but some benefits have been reported in the prevention of SCD after myocardial infarction and of AF, generally after long-course administration.

References

Calò L(1), Martino A(2), Tota C(2). The anti-arrhythmic effects of n-3 PUFAs.  Int J Cardiol. 170(2 Suppl 1):S21-7. doi: 10.1016/j.ijcard.2013.06.043. Dec 20 2013. Epub Sep 6 2013.

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