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Research: ALBUS and COLLEAGUES,
Listed in Issue 175
Abstract
ALBUS and COLLEAGUES, Department of Psychosomatics and Psychotherapy, University of Cologne, 50924, Cologne, Germany. christian.albus@uk-koeln.de evaluated the effects of a multimodal, behavioural intervention on myocardial perfusion (MP) and cardiac events, compared to standardized cardiologic care, in patients with stable CHD.
Background
Recent advances in drug therapy question as to the additional impact behavioural interventions may have on the prognosis of patients with clinically stable coronary heart disease (CHD).
Methodology
Seventy-seven CHD patients (age 54.2 +/- 6.9 years, male 87%) were randomly assigned to a behavioural intervention plus standardized cardiologic care (INT, n = 39) or standardized cardiologic care alone (CO, n = 38). MP was assessed by (201)Thallium MP-scintigrams (SPECT) at baseline, after 2, 3, and 7 years, respectively. Subsequent cardiac events (MI, PCI, CABG) were assessed using the cardiologists' charts.
Results
Sixty-five patients (84%) completed the study. In all patients, the course of MP was significantly better in INT analysis of variance (ANOVA group x time p = 0.001); this was also true for patients without subsequent PCI/CABG (ANOVA group x time p = 0.002). Incidence of cardiac events was significantly associated with INT (6 vs. 14; log rank test p = .047).
Conclusion
The study suggests additional long-term benefits of a behavioural intervention on myocardial perfusion and cardiac events in patients with stable CHD compared to standardized cardiologic care only.
References
Albus C, Theissen P, Hellmich M, Griebenow R, Wilhelm B, Aslim D, Schicha H and Kohle K. Long-term effects of a multimodal behavioral intervention on myocardial perfusion - a randomized controlled trial. International Journal of Behavioral Medicine. 16(3): 219-26. 2009.
