Research: WANG and COLLEAGUES,

Listed in Issue 249

Abstract

WANG and COLLEAGUES, 1. Center of Acupuncture and Moxibustion, Beijing Chinese Medicine Hospital Affiliated to Capital Medical University, Beijing 100010, China; 2. Department of Neurology, Dongfang Hospital Affiliated to Beijing University of CM; 3. Department of Neurology, Xuanwu Hospital Affiliated to Capital Medical University; 4. Beijing University of CM conducted a randomized case control study in order to analyze differences in therapeutic effects between acupuncture at acupoints and shallow needling therapy at nearby points upon relapsing-remitting multiple sclerosis (RRMS).

Background

To evaluate the differences in the therapeutic effects on relapsing-remitting multiple sclerosis (RRMS) at remission stage between acupuncture at acupoints and shallow needling therapy at the nearby points.

Methodology

Forty-two patients of RRMS were randomized into an observation group and a control group, 21 cases in each one. In the observation group, besides the basic treatment, acupuncture was applied according to WANG Leting's empirical prescriptions as "the empirical ten needles" "thirteen needles of the governor vessel" "twelve needles of hand and foot" as well as the symptomatic points. In the control group, the basic treatment was given. Additionally, the shallow needling therapy was given at the sites 0.2 to 0.3 cun lateral to the acupoints, and the arrival of qi was not required. In the two groups, acupuncture was given once a day for 5 days a week, continuously for 2 weeks. At the intervals of 2 weeks, totally the treatment of 3 months was required. The follow-up visit was conducted for 2 years. Separately, the scores of the expanded disability status scale (EDSS) before and in follow-up after treatment, the annual recurrent rate before and after treatment and recurrent interval after treatment were observed in the patients of the two groups.

Results

In the observation group, EDSS scores in 3-month and 6-month follow-up were reduced as compared with those before treatment (both P<0.05) and those in the 12-month and 24-month follow-up were increased (both P<0.05). In the control group, EDSS scores were increased in tendency continuously in 3-month, 6-month, 12-month and 24-month follow-up (all P<0.05). In each time point of follow-up, the different value of EDSS scores in the observation group was lower than that in the control group (P<0.05, P<0.01). The annual recurrent rates after treatment were reduced as compared with those before treatment in the two groups (both P<0.01) and the value in the observation group was lower than that in the control group (P<0.01). The recurrent interval in the observation group was longer than that in the control group[(441.56±65.37) d vs (382.78±59.33) d, P<0.01].

Conclusion

Acupuncture achieves the significant therapeutic effects on RRMS at the remission stage. This therapy relieves the symptoms of neural functional deficits, delays the time of occurrence and reduces the annual recurrent rate.

References

Wang C1, Chen Z2, Wang L1, Ma X1, Xing Y3, Li A4, Zhang F1, Zhang T1. [Relapsing-remitting multiple sclerosis at remission stage treated with acupuncture:a randomized controlled trial]. [Article in Chinese].  Zhongguo Zhen Jiu. 37(6):576-580. doi: 10.13703/j.0255-2930.2017.06.002. Jun 12 2017.

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