Positive Health Online

Abstract

UMESAWA and COLLEAGUES, Department of Public Health, Dokkyo Medical University School of Medicine, Mibu, Tochigi 321-0293, Japan studied the associations between vegetables and carotenes and prostate cancer risk in Japanese.

Background

The authors examined the associations of intakes of vegetables and carotenes with risk of prostate cancer in Japanese.

Methodology

A total of 15,471 Japanese men participating in the Japan Collaborative Cohort JACC study completed a questionnaire including food intake. Of them, 143 incident prostate cancers were documented. The authors examined the associations stated above by using Cox proportional hazard model.

Results

Vegetable intake was not associated with the risk of prostate cancer, but dietary alpha-carotene intake was. The multivariable hazard ratio (95% CI) in the secondary highest and highest quintiles of alpha-carotene intake was 0.50 (0.26-0.98) (P=0.043) and 0.46 (0.22-0.97) (P=0.041) (P for trend=0.224), respectively. Beta-carotene intake was not associated with the risk of prostate cancer.

Conclusion

Alpha-carotene intake was associated with lower risk of prostate cancer among Japanese.

References

Umesawa M, Iso H, Mikami K, Kubo T, Suzuki K, Watanabe Y, Mori M, Miki T, Tamakoshi A; JACC Study Group. Relationship between vegetable and carotene intake and risk of prostate cancer: the JACC study. Br J Cancer. 110(3):792-6. Feb 4 2014. doi: 10.1038/bjc.2013.685. Epub Oct 29 2013.   

Collaborators: Umesawa M, Iso H, Mikami K, Kubo T, Suzuki K, Watanabe Y, Mori M,  Miki T, Tamakoshi A.