Research: SUNKIREDDY and COLLEAGUES,

Listed in Issue 244

Abstract

SUNKIREDDY and COLLEAGUES,  (1)TERI-Deakin Nano Biotechnology Centre, The Energy and Resources Institute (TERI), Darbari Seth Block, IHC Complex, Lodhi Road, New Delhi 110003, India review the literature regarding natural antioxidants in future nanomedicine based therapy for cataract.

Background

Cataract is an eye disease of major human concern and its prevention is important to control the global incidences of blindness.

Methodology

The emergence of cataract in the eye lens by strong UV radiation and growing pollution could be effectively reduced by natural antioxidant biomolecules such as flavonoids, phenolic acids, carotenoids and vitamins.

Results

This goal can be achieved either by direct external use of antioxidant biomolecules in the form of topical application as an eye drops, food supplements or through nanobiotechnology based formulation without any side effects. In this manuscript, we have discussed the mechanisms of cataract formation and the preventive role of different classes of natural antioxidant biomolecules.

Conclusion

Further, role of nanobiotechnology to enhance therapeutic potential of these natural antioxidant molecules by enhancing solubility, stability, bioavailability and sustained release has been briefly discussed.

References

Sunkireddy P(1), Jha SN, Kanwar JR, Yadav SC. Natural antioxidant biomolecules promises future nanomedicine based therapy for cataract. Colloids Surf B Biointerfaces. 112:554-62. Dec 1 2013. doi: 10.1016/j.colsurfb.2013.07.068. Epub Aug 14 2013.

Munro Hall Clinic 2018

IJCA 2018 New Skyscraper

Scientific and Medical Network 2

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Snowdonia Charity Challenge 2018

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