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Research: SONKUSARE,
Listed in Issue 202
Abstract
SONKUSARE, Department of Obstetrics and Gynaecology, Kasturba Medical College, Manipal University, Manipal, Karnataka 576104, India. shipra_s18@rediffmail.com review the clinical management of hyperemesis gravidarum - extreme morning sickness.
Background
Hyperemesis gravidarum is a severe and disabling condition with potentially life-threatening complications.
Methodology
It is likely to have a multifactorial aetiology which contributes to the difficulty in treatment.
Results
Treatment is supportive with correction of dehydration and electrolyte disturbance, antiemetic therapy, prevention and treatment of complications like Wernicke's encephalopathy, osmotic demyelination syndrome, thromboembolism, and good psychological support.
Conclusion
There are abundant data on the safety of antihistamines, phenothiazines, and metoclopromide in early pregnancy and treatment should therefore not be withheld on the basis of teratogenicity concerns. Thiamine replacement is indicated in hyperemesis gravidarum to prevent development of Wernicke's encephalopathy.
References
Sonkusare S. The clinical management of hyperemesis gravidarum. [Review] Archives of Gynecology & Obstetrics. 283(6): 1183-92. Jun 2011.
Comment
This review is undoubtedly a good source of information for those seeking authoritative clinical information background about the pregnancy of the Duchess of Cambridge – Kate Middleton.
