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Research: SHIM and COLLEAGUES,
Listed in Issue 270
Abstract
SHIM and COLLEAGUES, 1. Department of Food and Nutrition, College of Medicine, Hanyang University, Seoul, South Korea studied the association between the risk of non-alcoholic fatty liver disease (NAFLD) and dietary pattern in patients who underwent cholecystectomy.
Background
The relationship between diet and non-alcoholic fatty liver disease (NAFLD) in patients with gallstone disease and in those who have a high risk for NAFLD has not been investigated. This study was conducted to investigate the association between the risk of NAFLD and dietary pattern in patients who underwent cholecystectomy. Additionally, the authors assessed the association between erythrocyte fatty acid composition, a marker for diet, and the risk of NAFLD.
Methodology
Patients (n = 139) underwent liver ultrasonography to determine the presence of NAFLD before laparoscopic cholecystectomy, reported dietary intake using food frequency questionnaire, and were assessed for blood fatty acid composition.
Results
Fifty-eight patients were diagnosed with NAFLD. The risk of NAFLD was negatively associated with 2 dietary patterns: consuming whole grain and legumes and consuming fish, vegetables, and fruit. NAFLD was positively associated with the consumption of refined grain, meat, processed meat, and fried foods. Additionally, the risk of NAFLD was positively associated with erythrocyte levels of 16:0 and 18:2t, while it was negatively associated with 20:5n3, 22:5n3, and Omega-3 Index.
Conclusion
The risk of NAFLD was negatively associated with a healthy dietary pattern of consuming whole grains, legumes, vegetables, fish, and fruit and with an erythrocyte level of n-3 polyunsaturated fatty acids rich in fish.
References
Shim P1, Choi D, Park Y. Association of Blood Fatty Acid Composition and Dietary Pattern with the Risk of Non-Alcoholic Fatty Liver Disease in Patients Who Underwent Cholecystectomy. Ann Nutr Metab:70(4):303-311. 2017 doi: 10.1159/000475605. Epub Jun 9 2017.
Comment
The above research demonstrated that the risk of non-alcoholic fatty liver disease (NAFLD) was negatively associated with a healthy diet with whole grains, legumes, vegetables, fish, and fruit and n-3 fatty acids in fish.
