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Research: QIN and COLLEAGUES,
Listed in Issue 314
Abstract
QIN and COLLEAGUES, (1)Department of Hematology, The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi, Hubei, P. R. China conducted a cross-sectional study to investigate the relationship between vitamin intake (including vitamins A, C, D, and E) and leukemia
Background
The present study assessed potential associations between vitamin intake and leukemia in a national sample of adults in the United States.
Methodology
A total of 5520 participants were included in this cross-sectional study to investigate the relationship between vitamin intake (including vitamins A, C, D, and E) and leukemia.
Results
Results revealed negative associations between vitamin C and E intake and leukemia, whereas associations between vitamin A and D and leukemia were not statistically significant. For vitamin C, compared with the first tertile, the odds ratio (OR) and corresponding 95% confidential interval (CI) was 0.90 (0.75-0.95) for the second tertile and 0.82 (0.61-0.90) for the third tertile (p < 0.01). For vitamin E, compared with the first tertile, the OR and 95% CI was 0.92 (0.80-0.96) for the second tertile and 0.86 (0.71-0.92) for the third tertile (p < 0.01). Furthermore, the inverse relationship between intake of vitamins C and E and leukemia were more evident for individuals ≥60 years of age and those with a body mass index >30 kg/m2.
Conclusion
Results of this study provide evidence suggesting that intake of vitamin C and E intake may decrease the prevalence of leukemia; however, further large-scale prospective cohort studies are needed to verify these findings.
References
Qin R(1), Xiang J(1), Zou L(1), Xiang G(1), Xiang H(1). Potential Associations Between Vitamin Intake and Leukemia: A Cross-Sectional Study. Nutr Cancer.;76(10):1001-1007. doi: 10.1080/01635581.2024.2383334. Epub Jul 24 2024. . 2024.
