Research: MASTEIKOVA and co-workers,

Listed in Issue 152

Abstract

MASTEIKOVA and co-workers, Department of Pharmaceutics, University of Veterinary and Pharmaceutical Sciences, Czech Republic, have assessed the antioxidant activity of Gingko, Echinacea, and Ginseng extracts.

Background

The aim of this study was to determine the amount of phenol compounds in tinctures prepared from Ginkgo leaves, Echinacea plant, and Ginseng roots and to evaluate the antioxidative activity of these preparations.

Methodology

The authors studied the antioxidative activity using two different laboratory tests.

Results

The results showed that the amount of phenol compounds in the studied tinctures differed and ranged between 114 to 340+/-29 gallic acid equivalents (GAE) mg/100 mL. The amount of phenol compounds in Ginkgo tincture was statistically significantly greater than that in Echinacea or Ginseng tinctures. The antioxidant activity of Ginkgo tincture was by 52.7% (p < 0.01) lower, compared to Echinacea tincture. Ginseng tincture was the weakest scavenger of free radicals. The inhibition of tyrosine nitration was by 34% (p < 0.01) greater in Echinacea tincture, compared to Ginkgo tincture. Ginseng tincture was the weakest inhibitor of tyrosine nitration. Tests showed that the antioxidant activity of Echinacea tincture was statistically significantly greater than that of Ginkgo or Ginseng tinctures.

Conclusion

The authors conclude that antioxidant activity is determined not only by phenol compounds, but also by a complex of other components of medicinal raw material.

References

Masteikova R, Muselik J, Bernatoniene J, Bernatoniene R. Antioxidative activity of Ginkgo, Echinacea, and Ginseng tinctures. Medicina (Kaunas, Lithuania) 43 (4): 306-309, 2007.

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