Research: KOTANI and colleagues, De

Listed in Issue 28


KOTANI and colleagues, Department of Anesthesiology, University of Hirosaki School of Medicine, Japan evaluated the analgaesic (pain-relieving) effect of Toki-shakyuaku-san (TSS), a herb used in Chinese Medicine in women suffering from dysmenorrhoea.



Women with a combination of Yin deficiency, cold and stagnated blood syndromes, determined using a diagnostic scoring system, and who were suffering from dysmenorrhea were treated either with TSS or placebo during 2 menstrual cycles double-blind and were followed for an additional 2 cycles.


Compared to women treated with placebo, women treated with TSS experienced a significant alleviation of dysmenorrhoea.


These results suggest that TSS is effective the treatment of dysmenorrhea in women with the above-named syndromes.


Kotani N et al. Analgesic effect of a herbal medicine for treatment of primary dysmenorrhea - a double-blind study. Am J Chin Med. 25(2): 205-12. 1997.

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