Research: HASHIKAWA and COLLEAGUES,

Listed in Issue 200

Abstract

HASHIKAWA and COLLEAGUES, Department of Orthopaedic Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan examined the risk factors for OA of the knee among Japanese community-dwelling women aged 40-89 years.

Background

Osteoarthritis (OA) of the knee is the most common form of arthritis and is a major contributor to functional impairment and reduced independence in older adults. In Japan, knee OA is a frequent cause of pain and disability, but few epidemiological studies have examined the demographic or lifestyle factors that influence OA of the knee. We examine the risk factors for OA of the knee among Japanese community-dwelling women aged 40-89 years (mean age 64.2, SD 9.6 years).

Methodology

Anteroposterior weight-bearing knee radiographs were graded according to the criteria described by Kellgren-Lawrence (K/L). We defined knee OA as a K/L grade of 2 or higher (using a 0-4 scale) based on the plain radiographs. History of knee injury, type of occupation, and daily intake of antioxidant nutrients including vitamin C and carotene were obtained from questionnaires.

Results

Among the 582 subjects, 195 women (33.5%) suffered from knee OA. Logistic regression analysis showed that older age [odds ratio (OR) 1.8, 95% confidence interval (95% CI) 1.6-2.1 per 5-year increase], higher body mass index (OR 2.2, 95% CI 1.7-3.0 per 5-unit increase) and previous knee injury (OR 3.1, 95% CI 1.7-5.6) were associated with knee OA. The occupation of farming and intake of antioxidant nutrients were not associated with knee OA.

Conclusion

Older age, obesity and previous knee injury represent independent risk factors for knee OA among Japanese women.

References

Hashikawa T, Osaki M, Ye Z, Tomita M, Abe Y, Honda S, Takamura N, Shindo H, Aoyagi K. Factors associated with radiographic osteoarthritis of the knee among community-dwelling Japanese women: the Hizen-Oshima Study. Source Journal of Orthopaedic Science. 16(1):51-5. Jan 2011.

Munro Hall Clinic 2019

IJCA 2018 New Skyscraper

Scientific and Medical Network 2

Cycle India 2020

Walk on the Wide Side Trek Kenya 2020

Big Heart Bike Ride South Africa 2020

top of the page