Research: GAO and COLLEAGUES,

Listed in Issue 253

Abstract

GAO and COLLEAGUES, 1. College of Acupuncture and Massage, Tianjin University of Traditional Chinese Medicine, No. 312, Anshan West Road, Nankai District, Tianjin, 300193, China; 2. Acupuncture Research Center, Tianjin University of Traditional Chinese Medicine, No. 312, Anshan West Road, Nankai District, Tianjin, 300193, China; 3. College of Acupuncture and Massage, Tianjin University of Traditional Chinese Medicine, No. 312, Anshan West Road, Nankai District, Tianjin, 300193, China. panxingfang@163.com ; 4. Acupuncture Research Center, Tianjin University of Traditional Chinese Medicine, No. 312, Anshan West Road, Nankai District, Tianjin, 300193, China. panxingfang@163.com; 5. College of Acupuncture and Massage, Tianjin University of Traditional Chinese Medicine, No. 312, Anshan West Road, Nankai District, Tianjin, 300193, China. guoyi_168@163.com ;

6. Acupuncture Research Center, Tianjin University of Traditional Chinese Medicine, No. 312, Anshan West Road, Nankai District, Tianjin, 300193, China. guoyi_168@163.com published a study protocol comparing the effects of distal-proximal point association and local distribution point association on controlling chemotherapy-induced nausea and vomiting (CINV) in patients in Tianjin, China.

Background

Acupuncture is beneficial for controlling chemotherapy-induced nausea and vomiting (CINV). However, the effect of different acupoint combinations on controlling CINV remains unknown. This study aims to compare the effects of distal-proximal point association and local distribution point association on controlling CINV.

Methodology

The study is a single-center, randomized controlled trial. A total of 240 participants will be randomly divided into four groups. The control group will receive standard antiemetic only, whereas three acupuncture groups will receive four electro-acupuncture treatments once a day with the standard antiemetic. Acupuncture group I and II will receive distal-proximal point association ("Neiguan (PC6) and Zhongwan (CV12)", and "Zusanli (ST36) and CV12", respectively); Acupuncture group III will receive local distribution point association ("Shangwan (CV13) and CV12"). The primary outcome measures are the frequency and distress of nausea and vomiting. The secondary outcome measures are the grade of constipation and diarrhoea, electrogastrogram, quality of life, etc. Assessment is scheduled from the day before chemotherapy to the fifth day of chemotherapy. Follow-ups are performed from the sixth day to the twenty-first day of chemotherapy.

Results

Results of this trial will help in evaluating the efficacy and safety of electro-acupuncture with different acupoint combinations in the management of CINV. Trial Registration: ClinicalTrials.gov identifier: NCT02478047 .

Conclusion

References

Gao L1,2, Chen B1,2, Zhang Q1,2, Zhao T1,2, Li B1,2, Sha T1, Zou J1,2, Guo Y1,2, Pan X3,4, Guo Y5,6. Acupuncture with different acupoint combinations for chemotherapy-induced nausea and vomiting: study protocol for a randomized controlled trial. BMC Complement Altern Med. 16(1):441. Nov 8 2016.

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