Research: FRYE and SILVERMAN

Listed in Issue 56


FRYE and SILVERMAN, Lancaster General Hospital Family Practice Residency Program, Pennsylvania, USA. reviewed (22 references) focused diagnosis and therapies for the multiple symptoms of premenstrual syndrome.




Premenstrual syndrome (PMS) is sometimes facetiously blamed when a woman behaves erratically. In fact, the cyclic symptoms of true PMS do cause significant difficulties in everyday life and relationships. This article is concerned with the criteria for diagnosing PMS and premenstrual dysphoric disorder and the authors describe medications, nutritional supplements and behaviour modifications that have proved effective for the relief of PMS symptoms.



Frye GM, and Silverman SD. Is it premenstrual syndrome? Keys to focused diagnosis, therapies for multiple symptoms. Postgraduate Medicine 107(5): 151-4, 157-9. May 2000.

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