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Research: DENG and COLLEAGUES,
Listed in Issue 312
Abstract
DENG and COLLEAGUES, (1)The First Clinical Medical College, Anhui University of Chinese Medicine, Hefei, Anhui, China; (2)The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, China; (3)The First Clinical Medical College, Anhui University of Chinese Medicine, Hefei, Anhui, China. tnkwyc@163.com ; (4)The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, China. tnkwyc@163.com .(5)The First Clinical Medical College, Anhui University of Chinese Medicine, Hefei, Anhui, China. zhangyudyx92@163.com ; (6)The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, China. zhangyudyx92@163.com .
(#)Contributed equally. Conventional meta-analysis and network meta-analysis were used to compare the clinical efficacies of acupuncture combined with Tuina and acupuncture-only in the treatment of peripheral facial paralysis (PFP)
Background
At present, traditional Chinese medicine treatment is considered safe for treating peripheral facial paralysis (PFP). Acupuncture-only and acupuncture combined with Tuina are widely used for this purpose. However, it is not clear whether acupuncture combined with Tuina is better for treating PFP than acupuncture-only. Conventional meta-analysis and network meta-analysis were used to compare the clinical efficacies of acupuncture combined with Tuina and acupuncture-only in the treatment of PFP.
Methodology
Randomized controlled trials (RCTs), with the subjects being patients with PFP and treatment interventions including acupuncture combined with Tuina, acupuncture-only, Tuina-only, placebo, single Western medicine, and steroids combined with other Western medicine were searched from both Chinese and English databases. The primary outcomes included Modified House-Brackmann (MHBN) scores and Sunnybrook Facial Grading System, whereas the secondary outcomes included cure time, Portmann scores, and physical function scale of Facial Disability Index, using conventional meta-analysis and network meta-analysis. The study included 22 RCTs with a sample size of 1814 patients.
Results
The results of conventional meta-analysis (MD = 16.12, 95%CI 13.13,19.10) and network meta-analysis (MD = 14.53, 95%CI 7.57,21.49) indicate that acupuncture combined with tuina was better than acupuncture-only in improving MHBN and shortening the cure time (MD = - 6.09, 95%CI - 7.70, - 4.49). Acupuncture combined with tuina was the optimal therapy for improving MHBN (SUCRA was 100%) and shortening the cure time (SUCRA was 100%).
Conclusion
The results of this meta-analysis indicate that acupuncture combined with tuina can significantly improve MHBN and shorten the cure time, compared with acupuncture-only. However, the current evidence is insufficient, and more high-quality clinical studies are needed. Registration: This study had been registered with PROSPERO (CRD42022379395). Conflict of interest statement: The authors declare that they have no conflict of interest. © 2024. The Author(s).
References
Deng X(1), Zhu H(1), Shi L(1), Li Y(1), Shi H(1)(2), Wu Y(#)(3)(4), Zhang Y(#)(5)(6). Comparison of the efficacy of acupuncture with tuina with acupuncture-only in the treatment of peripheral facial paralysis: a network meta-analysis. Intern Emerg Med ;19(3):839-858. doi: 10.1007/s11739-024-03562-2. Epub Mar 14 2024. Apr 2024.
