Positive Health Online
Your Country
![[Image: https://www.water-for-health.co.uk/]](/img/original/BannerAvatar/4046.12831f50177f8848ee87b8e94411d6b3.jpg "https://www.water-for-health.co.uk/")
![[Image: http://www.abundanceandhealth.co.uk]](/img/original/BannerAvatar/2836.df7d2315253110ff5b3a566f94871f99.jpg "http://www.abundanceandhealth.co.uk")
![[Image: https://peacegifts.shop/]](/img/original/BannerAvatar/3906.e1d1ebc07ce7530bbb3d6cf426966b6f.jpg "https://peacegifts.shop/")
![[Image: http://www.balens.co.uk]](/img/original/BannerAvatar/2148.50367fa908013fae0a7f1a171543ef92.jpg "http://www.balens.co.uk")
![[Image: http://www.drsgoodman.com/books-goodman/52-nutrition-and-cancer]](/img/original/BannerAvatar/1859.1296090fd8385e7ceff51c8011559097.jpg "http://www.drsgoodman.com/books-goodman/52-nutrition-and-cancer")
Research: DAVISON and co-workers,
Listed in Issue 93
Abstract
DAVISON and co-workers, School of Applied Medical Sciences and Sports Studies, University of Ulster Jordanstown, Belfast, UK, have studied exercise, free radicals, and lipid peroxidation in type I diabetes mellitus.
Background
It has been suggested that type I diabetes mellitus patients are more susceptible to resting and exercise-induced oxidative stress than healthy people, but to date there is no direct evidence that these patients have elevated levels of free radical species. The aim of this study was to investigate the levels of free radical species pre and post exercise in the venous blood of young men with type I diabetes mellitus, and to compare them with the same values in healthy young men.
Methodology
Electron Spin Resonance (ESR) spectroscopy was used to measure free radicals in venous blood of young men, both type I diabetic ones and matched controls. Supporting measures of lipid peroxidation, ambient blood glucose and selected antioxidants were also measured.
Results
Diabetes patients presented with greater concentrations of free radicals and lipid hydroperoxides compared to healthy controls (p = 0.05). There were no differences in other measures for lipid peroxidation. Vitamin E levels were lower in diabetics due to a large decrease during exercise (p = 0.05).
Conclusion
The authors suggest that the greater concentrations of free radicals found in diabetics are due to increased glucose auto-oxidation and/or a lower exercise-induced oxidation rate of the major antioxidant, vitamin E. The free radicals are thought to be secondary species derived from decomposition of lipid hydroperoxides.
References
Davison GW, George L, Jackson SK, Young IS, Davies B, Bailey DM, Peters JR, Ashton T. Exercise, free radicals, and lipid peroxidation in type I diabetes mellitus. Free Radical Biology and Medicine 33 (11): 1543-1551, Dec 1, 2002.
