Research: DAVIGLUS and colleagues,

Listed in Issue 20


DAVIGLUS and colleagues, Department of Preventive Medicine, Northwestern University Medical School, Chicago, IL USA studied the relationship of dietary beta-carotene and vitamin C to risk of prostate cancer.



The authors conducted a prospective study of 1,899 middle-aged men. Included were prostate cancer cases diagnosed in the first 24 years of follow-up as well as incident cases identified from the Health Care Financing Administration hospital and outpatient files during an additional 6 years of follow-up.


Prostate cancer developed in 132 men during the 30-year follow-up of this study. No indication was found that beta-carotene or vitamin C consumption was related to increased or decreased risk of prostate cancer. Associations between nutrient intakes and prostate cancer risk differed depending upon whether the cancer was diagnosed during the first 19 years of follow-up or the next 11 years of follow-up. Overall survival over the 30 years of follow-up was positively associated with intake of beta-carotene and vitamin C.


Beta-carotene and vitamin C consumption is positively related to overall survival.


DAVIGLUS ML et al. Dietary beta-carotene, vitamin C and risk of prostate cancer: results from the Western Electric Study. Epidemiology 7(5): 4727. Sep 1996.

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