Research: CARINCI and FELISATTI,

Listed in Issue 20

Abstract

CARINCI and FELISATTI, Cattedra di Chirurgia Maxillo-Facciale, Universita degli Studi, Ferrara review the evidence regarding the role of selenium in the prevention of oral and head and neck cancer. The authors write that during normal cellular metabolism, free oxygen radicals, which are extremely toxic, are constantly generated. However, these are rapidly eliminated by a series of metabolic steps involving certain enzymes including superoxide dismutase, catalase and glutathione peroxidase a selenium dependent enzyme. The hypothesis that free oxygen radicals may have carcinogenic properties may explain the link between low selenium levels and increased cancer morbidity. Therefore a correct selenium concentration in the blood plasma may represent a form of chemioprevention. The authors state that the concept of chemioprevention of carcinogenesis with inhibitory chemical compounds is particularly relevant to head and neck squamous cell cancer control because the incidence of metachronous second primary tumours in surviving patients with oral cancer is very high.

Background

Methodology

Results

Conclusion

References

Carinci F and Felisatti P. Selenium and oral cancer. Review of the literature. Minerva Stomatol 45(78): 3458. Jul-Aug 1996.

Munro Hall Clinic 2019

IJCA 2018 New Skyscraper

Scientific and Medical Network 2

Cycle India 2020

Walk on the Wide Side Trek Kenya 2020

Big Heart Bike Ride South Africa 2020

top of the page