Research: BRAZ and COLLEAGUES,

Listed in Issue 199

Abstract

BRAZ and COLLEAGUES, Universidade Federal da Paraiba, UFPB, Brazil. alessabraz@gmail.com

Background

Fibromyalgia is a chronic painful syndrome that affects up to 5% of the world population. It is associated with sleep and mood disorders, fatigue, and functional disability. Its pathogenesis involves a disorder of the central modulation of pain, impairment of the descending inhibitory system, and hyperactivity of substance P.

Methodology

Because of the extensive symptomatology of patients with fibromyalgia and its multifactorial pathogenesis, its ideal treatment requires a multidisciplinary approach including the association of pharmacological and non-pharmacological therapies.

Results

The pharmacological therapy currently recommended for the syndrome includes antidepressants, calcium-channel modulators, muscle relaxants, and analgesics. In most cases, the non-pharmacological treatment consists of patient education, supervised aerobic physical activity, and cognitive-behavioral therapy. However, many patients do not respond satisfactorily, or have side effects associated with the long-term use of drugs, in addition to reporting difficulties in adhering to a therapy based on exercises and physical medicine. Thus, physicians and patients are increasingly interested in an alternative and complementary therapy for fibromyalgia.

Conclusion

This review approaches the different therapeutic modalities used in fibromyalgia, emphasizing the evidence of non-pharmacological therapy and use of alternative and complementary medicine for these patients.

References

Braz Ade S, de Paula AP, Diniz Mde F and de Almeida RN. Non-pharmacological therapy and complementary and alternative medicine in fibromyalgia. [Review] Source Revista Brasileira de Reumatologia. 51(3):269-82. Jun 2011.

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