Research: BATTISTI and colleagues,

Listed in Issue 55

Abstract

BATTISTI and colleagues, OU of Neurometabolic Disease, Institute of Neurological Sciences, University of Sienna, Italy studied vitamin E serum levels in patients with gastric cancer.

Background

The authors write that alpha-tocopherol has been reported to play an important role against oxidative damage and in the inhibition of cell transforming and mutagenesis.

Methodology

The authors analyzed vitamin E serum levels in 51 gastric cancer patients in different stages of the disease, and in 49 age-matched controls.<br>

Results

All patients had normal values of alpha-tocopherol; however, when patients were grouped according to histotype of gastric lesions, there was a significant vitamin E increase in diffuse gastric cancer histotype compared to the intestinal histotype.

Conclusion

These results suggest that there may be a correlation between vitamin E serum levels and gastric cancer histotype.

References

Battisti C et al. Vitamin E serum levels and gastric cancer: results from a cohort of patients in Tuscany, Italy. Cancer Letters 151(1): 15-8. 3 Apr 2000.

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