Research: ADAMSEN and others,

Listed in Issue 134

Abstract

ADAMSEN and others, The University Hospitals Centre for Nursing and Care Research, Department 7331, The University Hospital of Copenhagen, Blegdamvej 9, 2100, Copenhagen, Denmark, have investigated the effects of an exercise programme on the wellbeing of cancer patients.

Background

The aim of this study was to investigate the impact of a multidimensional exercise intervention on cancer patients undergoing chemotherapy.

Methodology

The intervention comprised resistance and fitness training, massage, relaxation and body-awareness training. It focussed on physical capacity; one-repetition maximum (1RM) and maximum oxygen uptake (VO2Max), activity level, general well-being and quality of life. 82 cancer patients were included. The patients trained in mixed groups for 9 hours weekly for 6 weeks. Physical capacity, physical activity level and psychosocial well-being as measured by the Medical Outcomes Study 36-item Short-Form Health Survey and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30 were assessed pre- and post-intervention.

Results

Highly significant increases were achieved in muscular strength (p<0.001), physical fitness (p<0.001) and physical activity levels (p<0.001). The patients reported significant reduction in treatment-related symptoms, i.e., fatigue (p=0.006) and pain (p=0.03). Highly significant improvements were observed in physical functioning (p<0.001) and role functioning (p<0.001). Even patients with advanced disease were able to improve their results after 6 weeks.

Conclusion

This study indicates significant clinically meaningful improvements for cancer patients undergoing chemotherapy. The exact role of the intervention has to be defined in a randomized controlled design.

References

Adamsen L, Quist M, Midtgaard J, Andersen C, Moller T, Knutsen L, Tveteras A Rorth M. The effect of a multidimensional exercise intervention on physical capacity, well-being and quality of life in cancer patients undergoing chemotherapy. Supportive Care in Cancer 14 (2): 116-127, Feb 2006.   

Comment

This exercise program could be integrated into cancer treatment programs to improve the wellbeing of cancer patients.

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