Research: SMITH and colleagues,

Listed in Issue 102


SMITH and colleagues, Department of Obstetrics and Gynaecology, The University of Adelaide, Adelaide, Australia,, report on a randomized controlled trial of ginger against nausea and vomiting in pregnant women.


The aim of the trial was to assess whether ginger is equivalent to pyridoxine hydrochloride (vitamin B6) as a treatment of nausea and vomiting in pregnancy.


In this randomized, single-blinded trial, 291 women less than 16 weeks pregnant took either 1.05 g ginger or 75 mg vitamin B6 daily for 3 weeks. Differences in nausea and vomiting were assessed for both groups at days 7, 14, and 21.


Ginger proved to be equivalent to vitamin B6 in reducing nausea, retching, and vomiting, averaged over time, with no evidence of difference over the 3 time points.


For pregnant women experiencing morning sickness in pregnancy, ginger is as good a treatment as vitamin B6.


Smith C. Crowther C, Willson K, Hotham N, McMillian V. A randomized controlled trial of ginger to treat nausea and vomiting in pregnancy. Obstetrics and Gynecology 103 (4): 639-645, Apr 2004.

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