Research: SEDDON,

Listed in Issue 144


SEDDON, Epidemiology Unit, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA,, has reviewed (47 references) nutritional supplements and eye disease.

Abstract: The prevalence and effects of age-related macular degeneration and cataract are increasing dramatically as the proportion of elderly in our population continues to rise. A multivitamin-multimineral supplement with a combination of vitamin C, vitamin E, beta-carotene, and zinc (with cupric oxide) is recommended for age-related macular degeneration but not cataract. Weak support exists for multivitamins or other vitamin supplements from observational studies of cataract. The results of observational studies suggest that a healthy lifestyle with a diet containing foods rich in antioxidants, particularly lutein and zeaxanthine, as well as n-3 fatty acids, appears beneficial for age-related macular degeneration and possibly cataract. The Age-Related Eye Disease Study II will evaluate some of these additional nutrients as dietary supplements in a randomized trial.






Seddon JM. Multivitamin-multimineral supplements and eye disease: age-related macular degeneration and cataract. American Journal of Clinical Nutrition 85 (1): 304S-307S, Jan 2007.


In these days of CODEX and EU Directives about to restrict the availability of nutritional supplements, it is important to note that the above research regarding nutritional supplements and macular degeneration and cataract eye conditions is being conducted by the Epidemiology Unit of Harvard Medical School.

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