Research: POTTER, Fred Hutchinson C

Listed in Issue 24

Abstract

POTTER, Fred Hutchinson Cancer Research Center and University of Washington, Seattle USA writes that vegetables and fruits are associated with a reduced risk of cancers, including and especially lung cancer. Compounds which are possibly protective may include a wide number of phytochemicals, but a great deal of attention has been focussed upon the single agent: beta-carotene. In certain clinical trials (see Pietinen P et al, in the Heart Research Update section), beta-carotene has been shown not to be an effective agent and perhaps to increase risk. The author presents possible explanations, and discusses the danger of reductionist approaches to the explanation of the complex nutrition-related biology of cancer.

Background

Methodology

Results

Conclusion

References

Potter JD. Beta-Carotene and the role of intervention studies. Cancer Lett 114(1-2): 329-31. Mar 19 1997.

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