Research: NOLL and COLLEAGUES, 

Listed in Issue 269


NOLL and COLLEAGUES,  1. Department of Anesthesiology Stony Brook Medicine, Stony Brook, NY, USA. ; 2. Institut de Chirurgie Guidee par l'Image, IHU Hopitaux Universitaire de Strasbourg, Strasbourg, France. ; 3. Service d'Anesthesie Reanimation Hautepierre - CCOM - CMCO, Hopitaux Universitaires de Strasbourg, Strasbourg, France. ; 4. C.C.O.M., 10 avenue Achille Baumann, 67400, Illkirch-Graffenstaden, France. ; 5. Department of Anesthesiology Stony Brook Medicine, Stony Brook, NY, USA; 6. Department of Surgery Stony Brook Medicine, Stony Brook, NY, USA investigated the clinical benefits of acupressure therapy on quality of recovery and life in hospitalized patients following surgical treatment.


Acupressure therapy may be potentially beneficial in improving postoperative symptoms like postoperative nausea and vomiting (PONV), pain and sleep disorder and improving postoperative quality of recovery. The primary aim of this study is to investigate the efficacy of acupressure therapy on postoperative patient satisfaction and quality of recovery in hospitalized patients after surgical treatment.


This three-group, parallel, superiority, blinded, randomized controlled trial will test the hypothesis that a combination of PC6, LI4 and HT7 acupressure is superior to sham or no intervention for improving postoperative quality of recovery in hospitalized patients. A minimum of 150 patients will be randomly allocated to one of the three experimental groups: control (no visit), light touch (sham acupressure) or active acupressure therapy in a 1:1:1 ratio. Interventions will be performed three times a day for 2 days. Patient satisfaction, quality of recovery, PONV and pain will be measured during the 3 days following randomization. The study protocol was approved by the Stony Brook University Institutional Review Board on 21 March 2016. Written informed consent will be recorded from every consented patient.



This study has the potential to improve the recovery of hospitalized patients by adding knowledge on the efficacy of acupressure therapy in this setting. A multipoint acupressure protocol will be compared to both a no intervention group and a light touch group, providing insight into different aspects of the placebo effect. Trial Registration:, NCT02762435 . Registered on 14 April 2016.


Noll E1,2,3,4, Shodhan S5, Madariaga MC5, Page CR5, Santangelo D5, Guo X5, Al Bizri E5, Pryor AD6, Romeiser J5, Bennett-Guerrero E5. Randomized trial of acupressure to improve patient satisfaction and quality of recovery in hospitalized patients: study protocol for a randomized controlled trial. Trials;18(1):110. doi: 10.1186/s13063-017-1839-1. Mar 7 2017.

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