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Research: LIU and colleagues,
Listed in Issue 127
Abstract
LIU and colleagues, Gerontological Department, The First Hospital affiliated to Tianjin College of Traditional Chinese Medicine, 314 West Anshan Avenue, China, have found that acupuncture ameliorates oxidative damage in the brains of rats who have had strokes.
Background
The aim of this study was to investigate the effects of acupuncture on cognitive deficits and oxidative stress in cerebral multi-infarction rats.
Methodology
Behavioural animal study.
Results
The results showed that acupuncture treatment attenuated memory impairment induced by cerebral multi-infarction, as evaluated by shortened escape latency and increased swimming time of rats with memory impairment in the target quadrant. The data additionally suggested that acupuncture treatment ameliorated oxidative injuries induced by cerebral multi-infarction by increasing the activities of the enzymes superoxide dismutase and glutathione peroxidase in the hippocampus. Further investigation revealed that acupuncture treatment significantly increased the expression of superoxide dismutase in the hippocampus of the impaired rats.
Conclusion
The findings demonstrate that acupuncture can exert beneficial effects on the brains of rats that have experienced strokes.
References
Liu CZ, Yu JC, Zhang XZ, Fu WW, Wang T, Han JX. Acupuncture prevents cognitive deficits and oxidative stress in cerebral multi-infarction rats. Neuroscience Letters 393 (1): 45-50, Jan 23, 2006.
