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Research: DE STEFANI and colleagues
Listed in Issue 37
Abstract
DE STEFANI and colleagues, Registro Nacional de Cancer, Instituto Nacional de Oncologia, Montevideo, Uruguay studied the relationship between dietary sucrose intake and colorectal cancer .
Background
Methodology
The authors conducted a case control study during 1992-96. 289 cases and 564 controls were admitted for diagnosis or treatment in 4 major hospitals in Montevideo and considered eligible for the study.
Results
Total sucrose intake was associated with a positive gradient of risks; the odds ratio (OR) for the uppermost quartile of intake was 2.18. Glucose intake was associated with a small and non-significant increase in risk (OR = 1.46). An interaction between sucrose and protein intake was discovered; the OR for high intakes of sucrose and protein was 6.07.
Conclusion
References
De Stefani E et al. Sucrose as a risk factor for cancer of the colon and rectum: a case-control study in Uruguay. Int J Cancer 75(1): 40-4. 5 Jan 1998.
