Research: BIRMESSER and STOLT,

Listed in Issue 145


BIRMESSER and STOLT, Klinik fur Sportorthopadie/Sporttraumatologie, Universitatsklinikum Freiburg, Freiburg, Germany,, have reviewed (53 references) the homeopathic medicine Zeel comp. and its use for the treatment of arthritis.

Abstract: Zeel comp. N (Zeel) is a homeopathic medication that has been widely used for many years for the treatment of arthritic disorders in a large number of countries worldwide. In recent years, a growing body of clinical and molecular evidence has been accumulating that sheds light on the possible antiarthritic effects of this preparation. A number of studies report anti-inflammatory effects from Zeel. In vitro studies have indicated Zeel-mediated inhibition of the pathways involving the enzymes cyclooxygenase-1 and -2, and also the 5-lipoxygenase pathways, affecting levels of both eicosanoids and leukotrienes. Thus, Zeel may reduce the main two classes of molecules responsible for arthritic pain and inflammation. This review describes recent research on Zeel and discusses the need for further studies to clarify the role of the compound in the antiarthritic armamentarium of complementary medicine.






Birnesser H, Stolt P. The homeopathic antiarthitic preparation Zeel comp. N: a review of molecular and clinical data. Explore-The Journal of Science & Healing 3 (1): 16-22, Jan-Feb 2007.

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