Research: AMMERSCHLAGER and colleagues,

Listed in Issue 125

Abstract

AMMERSCHLAGER and colleagues, Facharzt fur Allgemeinmedizin, Aschaffenburg, Germany, have compared a homeopathic remedy (Euphorbium compositum nasal drops SN) and an allopathic one in the treatment of sinus infection.

Background

The aim of the study was to determine whether the therapeutic effects of the homeopathic complex remedy Euphorbium compositum nasal drops SN are comparable to those of xylometazoline with respect to efficacy and tolerability.

Methodology

In this open, multicentre, prospective, active-controlled cohort study, patients with inflammatory processes and diseases of the upper respiratory tract were enrolled. The primary outcome was to demonstrate non-inferiority of the homeopathic complex remedy to xylometazoline.

Results

Clinically relevant reductions in the intensities of disease-specific symptoms were observed with both therapies. Non-inferiority of the homeopathic complex remedy to xylometazoline could be shown for all studied variables and in no case did the lower boundary of the 95% confidence interval cross the threshold of 0.5 score points. Tolerability was good with for both therapies.

Conclusion

This cohort study indicates a comparable efficacy and tolerability profile of the homeopathic complex remedy Euphorbium compositum nasal drops SN and the reference substance xylometazoline in patients with inflammatory processes and diseases of the upper respiratory tract.

References

Ammerschlager H, Klein P, Weiser M, Oberbaum M. Treatment of inflammatory diseases of the upper respiratory tract — comparison of a homeopathic complex remedy with xylometazolinee. Forschende Komplementarmedizin und Klassische Naturheilkunde 12 (1): 24-31, Feb 2005.

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