Research: AABEL and colleagues,

Listed in Issue 67


AABEL and colleagues, Institute of General Practice and Community Medicine, Department of General Practice, University of Oslo, Norway attempted to reproduce the previously reported positive results of a nuclear magnetic resonance (NMR) analysis of homeopathic solutions.


The efficacy of homeopathy is controversial. NMR has been used to study homeopathic solutions, producing provocative results.


1H NMR spectra were recorded for Sulphur D4, diluted and succussed up to D30 (called potentization) at two different frequencies (300 and 500 MHz). The Sulphur solution had been potentiated according to homeopathic principles with deionized water and alcohol. Water proton T1 relaxation measurements were also performed at 20 MHz for the different potentiated Sulphur solutions. Similarly, the homeopathic remedy Betula alba 30c (birch pollen extract) and appropriate control solutions (deionized water, unsuccussed solutions, and placebo globules) were measured, both with frequencies giving spectra and T1 relaxometry.


The Sulphur remedies showed identical one-dimensional proton spectra (1H NMR) at 300 and 500 MHz, regardless of dilution/succussion stage, from D4 to D30. Betula 30c as a potentiated solution and its controls showed identical spectra . There were no statistically significant differences in longitudinal (T1) relaxation times between deionized water and Sulphur D10 to D30 preparations. The Sulphur D4 preparation showed a shorter T1, which could be ascribed to the higher microviscosity within the sample matrix caused by the high concentration of dissolved material. T1 values of Betula alba 30c preparation (in globular form) and control placebo globules were identical .


The investigators were unable to reproduce previously published results from NMR research indicating differences between homeopathic solutions and control samples.


Aabel S et al. Nuclear magnetic resonance (NMR) studies of homeopathic solutions. The British Homoeopathic Journal 90 (1): 14-20. Jan 2001.

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